Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0309572
PubChem CID
Molecular Formula
C10H13N3
Molecular Weight
175.235 g/mol
Synonyms/Alias
[(S;E)-5-(2-(Pyrrolidin-3-yl)vinyl)pyrimidine; 753015-45-1; SCHEMBL1333776; SCHEMBL1333778; CHEMBL1789752; PD161643]
InChI Key
FNEHSHNEXMPCLJ-GPYPMJJRSA-N
InChI
InChI=1S/C10H13N3/c1(9-3-4-11-5-9)2-10-6-12-8-13-7-10/h1-2,6-9,11H,3-5H2/b2-1+/t9-/m1/s1
IUPAC Name
5-[(E)-2-[(3S)-pyrrolidin-3-yl]ethenyl]pyrimidine
CAS Number
753015-44-0

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

26 27 0 0 0 0 0 0 0 0999 V2000
-2.4756 -1.0873 0.6719 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.7812 -0.4642 0.2116 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.4633 0.649...

Experimental Data

Activity Data

Target Ion Channel
Neuronal acetylcholine receptor subunit alpha-6/beta-2
Uniprot Accession Number
Function
Agonist
Species
Mus musculus (Mouse)
IC50
N/A (Not available)
EC50
EC50: 530 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.5
Holding Potential
Not specified
Temperature
22 °C
Test Method
Binding assay ([125I] alpha-Conotoxin MII)
Test Species
Not specified

Binding Information

Binding Site
Extracellular domain
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
13
Rotatable Bonds
2
logP
1.0993
Complexity
52.0427
TPSA (Ų)
37.81
H-Bond Donors
1
H-Bond Acceptors
3
Ring Count
2
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